NEET MDS

The Power Course

Which coagulant factor is activated by both extrinsic and intrinsic pathways



Choices

1 ) Factor VIII
2 ) Factor IX
3 ) Factor VII
4 ) Factor X

Explanation



Coagulation Pathway

Coagulation system has two pathways for coagulation, namely extrinsic and intrinsic pathways.

Activation of Factor X happens by both pathways i.e. intrinsic and extrinsic

Intrinsic pathway

The initial step is the activation of factor XII. This activates factor XI. Activated factor XI activates factor IX. Activated factor IX forms complex with activated factor VIII.

Factor VIII is a bound to von Willebrand factor. Factor VIII activation happens by separation of Von Willebrand factor.

A complex formed activated factor VIII and factor IX activates factor X

Extrinsic Pathway

This is triggered by the release of tissue thromboplastin. This activates factor VII. Activated factor VII activates factor X.

Activated Factor X

Activated Factor X converts prothrombin to Thrombin. This Thrombin converts fibrinogen to fibrin.


Answer

Factor X

Last Modified : 25-Dec-2019

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