The Power Course

Cheyne-Stokes Respiration


1 ) Decreased sensitivity to hypoxia
2 ) Hyperdynamic circulation can trigger
3 ) Hyperventilation with periods of apnea
4 ) All of the above


Periodic breathing or Chyne-stoke breathing occurs in diseases.

Causes of Chyne-stoke breathing


Heart failure

Diseases of Brain



Some people have increased sensitivity to CO2. This is due to the disruption of neural pathways that inhibit respiration. There is an over-response to CO2 leading to hyperventilation, this is followed by apnea where CO2 builds up leading to over response of hyperventilation thus cycle continues.

Chyne stroke breathing can occur in patients with heart failure. This is due to slow circulation. Due to slow circulation, there is prolonged circulation time between lung and brain. CO2 fall in capillaries of lung take longer time to show up in the brain, by then the brain sends a signal for hyperventilation, thus leading to more fall in CO2 levels, which leads to apnea and an increase in the level of CO2. Thus the cycle continues. Respiratory control system oscillates because of the negative feedback loop from lungs to the brain is abnormally long.


Hyperventilation with periods of apnea

Last Modified : 25-Dec-2019

Previous MCQ
Next MCQ
Enter your email address:



Previous Years Question Papers