An example of a static cell population:
Based on the mitotic activity, adult somatic cells populations can be classified as:
1. Statistic cell population
2. Stable cell population
3. Renewing cell population
i) Slow renewing populations
ii) Rapidly renewing populations
1. Static cell population:
It consists of cells that do not divide anymore.
Eg: Cells of the central nervous system, cells of skeletal and cardiac muscles that divide rarely.
2. Stable cell population:
They include cells that divide episodically at a slow rate to maintain normal tissue or any cell injury can stimulate cell renewal.
Eg: Periosteal and perichondral cells, smooth muscle cells, endothelial cells and fibroblasts of loose connective tissue.
3. Renewing cell population:
These cells show regular mitotic activity. They may be either slowly renewing or rapidly renewing cells.
i) Slowly renewing cells:
Eg: Smooth muscle cells of hollow organs, fibroblasts of the uterine wall, epithelial cells of the lens of the eye.
ii) Rapidly renewing cells:
Eg: Blood cells, epithelial cells, dermal fibroblasts and epithelial and subepithelial fibroblasts of the mucosal lining of the alimentary tract.